Each cell of the human body contains two meters of DNA. The whole secret lies in the intricate three-dimensional arrangement that allows DNA strands to be efficiently organized and compacted within ...

Using the Hubble Space Telescope (HST), astronomers have observed a supermassive galactic open cluster designated Westerlund ...

Similar attempts to reproduce the binding mode of the molecular glue and structure of the ternary complex formed therein were carried out for the molecular glue-mediated ternary system as in PDB ID: ...

CRL4 (Cullin-RING ubiquitin ligase) is an E3 ubiquitin ligase, composed of three subunits DDB1, cullin 4 (CUL4), and regulator ... expressed-developmentally-down-regulated-8 (NEDD8) has a structure ...

Our results show the importance of the dynamic features in protein structure and how the linker region of a PROTAC may contribute to protein motions to achieve PROTAC-mediated POI degradation.

Interneurons have a multipolar structure that allows them to receive multiple signals and then send a unified command to another neuron. In this way, you can think of interneurons as traffic ...

Summary: Entrepreneurs often grapple with the decision of whether to structure their business as a Company or a Limited Liability Partnership (LLP). Both offer the advantage of limited liability and ...

Sussex Drug Discovery Centre, School of Life Sciences, University of Sussex, Falmer BN1 9QJ, U.K. Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, 1 James ...