Studies have demonstrated that the mRNA expression levels of SMC1A, SMC1B, SMC2, SMC4, and SMC6 are significantly overexpressed in HCC, and the protein levels of SMC1A, SMC2, SMC3, SMC4, SMC5, and ...
Both are formed when the Smc5 and Smc6 head domains interact. In common with all SMC complexes, the ATP binding pockets have an arginine finger, which is proposed to regulate DNA-dependent ATP ...
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