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(A) This patient had a severe small-fiber sensory and autonomic polyneuropathy ... Multifocal diabetic neuropathy. Cross section of a paraffin-embedded superficial peroneal nerve specimen ...

According to a case–control study published in Neurology, the expression of proinflammatory cytokines is elevated in the affected skin of patients with small-fiber neuropathy (SFN).

In some cases, treatment of the underlying disease will improve the neuropathy and symptoms. In other situations, such as many cases of small fiber neuropathy, where no cause can be identified ...

the neuropathy symptom score, and quantitative sensory function tests that indicate small-fiber denervation. A Neuropad was applied to the plantar aspect of one great toe and the color change was ...