RTCB is required for the splicing of both tRNA and XBP1 mRNA, whereas the DDX1 enzymatic activity is specifically required for tRNA splicing in vivo. Snaebjornsson et al. explore a selective ...

A "groundbreaking" £1.65 million treatment has been approved for use on the NHS, offering patients with severe sickle cell disease some hope of a cure. It is believed around 1,700 people could be ...

Our independent appraisal committee has approved the use of gene editing therapy exagamglogene autotemcel (exa-cel) for use in the NHS in England, providing a potential cure for some people with ...

A cutting-edge gene therapy has been approved for NHS use for some patients with severe sickle cell disease. Casgevy, also known as exa-cel, was the first treatment to be licensed using gene ...

A sickle cell disease “cure” is to be offered to NHS patients for the first time. The £1.65 million gene therapy called exa-cel, also known under the brand name Casgevy, uses a Nobel Prize ...

Would the transplant work? What would it look like to have a successful stem cell transplant? Would it be a cure for my sickle cell disease? It was a decision I could think about making because my ...

LONDON, Jan 31 (Reuters) - Britain's National Health Service (NHS) will provide a cutting-edge gene therapy that aims to cure sickle cell disease, the National Institute for Health and Care ...

Sickle Cell Trait Does Not Cause "Sickle Cell Crisis" Leading to Exertion-Related Death: A Systematic Review. Blood Journal , 2025; DOI: 10.1182/blood.2024026899 Cite This Page : ...

It feels like the Splinter Cell remake has been on its way for a while now, which isn't helped by the fact it's been over three years since we heard anything official about the game. From what we ...

The iconic game show Hollywood Squares is back with a new look, a new center square and a new host. Nate Burleson, the CBS Mornings host, former NFL wide receiver and current analyst for CBS will ...

Sickle cell anaemia occurs when red blood cells change shape under low oxygen conditions, transforming into a sickle shape that can block blood flow. This blockage can result in pain in the ...