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And then I heard you laugh.” So I’ve been trying never to laugh ever again. Never, ever be funny, Seth Rogen. Seth: Yeah, I’ll hide my laugh. That’s an ironic thing for someone like me to ...

(Left-right:) Seth Rogen and Beyoncé ... “I think that was the night they were like, f--- this,” jokes Rogen with a laugh. “‘Let's get the f--- out,’” quips Eichner.

Lauren Miller Rogen and her husband, Seth Rogen, are best known for making people laugh. Their latest cinematic endeavor, though, addresses a subject seemingly devoid of humor: Alzheimer’s disease.