Department of Nuclear Medicine, Xinqiao Hospital, Army Medical University, Chongqing 400037, China School of Medical Imaging, North Sichuan Medical College, NanChong 637100, China Department of ...

This study reports that activation of TFEB promotes lysosomal exocytosis and clearance of cholesterol from lysosomes, the strength of evidence for which is convincing with appropriate and validated ...

Gene-engineered immune cell therapies have partially transformed cancer treatment, as exemplified by the use of chimeric antigen receptor (CAR)-T cells in certain hematologic malignancies. However, ...

Several studies have established the participation of important signaling pathways, including Wnt, Notch, BMP/TGF-β, PDGF, IGF, FGF, Ca2+, JNK, MARK and mTOR/S6K1/S6 pathway (Majidinia et al., 2018).

Ageing is associated with physical decline and the development of age-related diseases such as metabolic disorders and cancer. Few conditions are known that attenuate the adverse effects of ageing, ...