eLife24d
MftG is crucial for alcohol metabolism of mycobacteria by linking mycofactocin oxidation to respiration
This valuable work examines the role of the oxidoreductase MftG in Mycolicibacerium smegmatis alcohol metabolism. A solid set of data is presented to show that, in the context of ethanol metabolism, ...
eLife1mon
The protective roles of Eugenol on type 1 diabetes mellitus through NRF2 mediated oxidative stress pathway
This useful study partially succeeds in providing solid evidence in support of the therapeutic potential of the plant-derived compound eugenol for ameliorating symptoms associated with STZ-induced ...
Science Daily1mon
The ins and outs of quinone carbon capture
Led by former Harvard postdoctoral fellow Kiana Amini, now an assistant professor at University of British Columbia, the study outlines the detailed chemistry of how an aqueous, quinone-mediated ...
C&EN1mon
Long-Term Exposure to Tire-Derived 6-PPD Quinone Causes Neurotoxicity and Neuroinflammation via Inhibition of HTR2A in C57BL/6 Mice
School of Basic Medical Sciences, Shandong Second Medical University, 7166 Baotong West Street, Weicheng District, Weifang, Shandong 261053, China Affiliated Hospital of Shandong Second Medical ...
Frontiers1y
Genome sequencing and metabolic network reconstruction of a novel sulfur-oxidizing bacterium Acidithiobacillus Ameehan
Fifteen genes were identified in sulfur metabolism, including SQR (sulfide: quinone oxidoreductase), thiosulfate quinone oxidoreductase (TQO), tetrathionate hydrolase (TetH), sox system, sulfur ...
Frontiers2y
Nrf2 Activation With CDDO-Methyl Promotes Beneficial and Deleterious Clinical Effects in Transgenic Mice With Sickle Cell Anemia
A phase-1 open label dose-escalation study with the Nrf2 activator sulforaphane (SFN), increased the mRNA expression of heme oxygenase (HO-1) and NAD(P)H: Quinone Oxidoreductase (NQO1) in whole blood ...