The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and ...

Greatwall, a conserved MAST-like kinase with crucial mitotic entry functions, is curiously absent in worms. Here, the single ...

This content introduces the physiological and pathological importance of protein kinases, kinase inhibitors approved for ...

Cystic fibrosis is a life-threatening disease predominantly with respiratory symptoms. Most of the subjects with the disease harbor the F508del variant in the CFTR gene that causes the protein to ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

Designing Life with AI" is a cross-disciplinary MAKE project in which EPFL students get a chance to explore the research ...

Furthermore, they have demonstrated that it is possible to reprogram other cancer cells to become dependent on this enzyme – ...

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

Study shows that cannabidiol (CBD) enhances endurance exercise in mice by reshaping gut microbiota, boosting mitochondrial ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

An important cellular pathway is the mitogen-activated protein kinase (MAPK ... Insofar as cancer is concerned, DUSP6’s function appears to vary depending on the cancer type.