2d
News Medical on MSNUnfolded protein response: A key regulator of intestinal health and diseaseThe intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and ...
Greatwall, a conserved MAST-like kinase with crucial mitotic entry functions, is curiously absent in worms. Here, the single ...
This content introduces the physiological and pathological importance of protein kinases, kinase inhibitors approved for ...
Cystic fibrosis is a life-threatening disease predominantly with respiratory symptoms. Most of the subjects with the disease harbor the F508del variant in the CFTR gene that causes the protein to ...
Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.
Furthermore, they have demonstrated that it is possible to reprogram other cancer cells to become dependent on this enzyme – ...
1d
News Medical on MSNCBD boosts endurance in mice by reshaping gut bacteria and enhancing muscle performanceStudy shows that cannabidiol (CBD) enhances endurance exercise in mice by reshaping gut microbiota, boosting mitochondrial ...
5d
The Brighterside of News on MSNScientists create advanced sense-and-respond systems that mimic natural cellular behaviorProtein phosphorylation is a cornerstone of cellular communication, orchestrating rapid and precise responses to ...
Ono picked up Romvimza—previously known by its active ingredient vimseltinib—from its $2.4 billion acquisition of Deciphera ...
4d
StudyFinds on MSNLake swimming in Iowa led to rare Legionnaires’ disease case that puzzled doctors for daysIn A Nutshell While Legionnaires’ disease typically makes headlines when linked to building water systems, this case shows ...
Solid Biosciences (SLDB) announced initial data from the Phase 1/2 INSPIRE DUCHENNE trial evaluating SGT-003, a next-generation gene therapy ...
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