Greatwall, a conserved MAST-like kinase with crucial mitotic entry functions, is curiously absent in worms. Here, the single ...

A new discovery from an international collaborative research team has solved the mystery of how cells turn on their recycling ...

A new discovery from an international collaborative research team has solved the mystery of how cells turn on their recycling process and create ...

Medically reviewed by Smita Patel, DO Duchenne muscular dystrophy (DMD) is a rare neurological condition that causes severe muscle weakness and intellectual disability. DMD is an inherited (passed ...

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and ...

All biological function is dependent on how different proteins interact with each other. Protein-protein interactions ...

E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure that the tag is added to the right protein; as such, hundreds of specific ...

Researchers at the University of Tsukuba have reported on the structure and light energy transfer efficiency of a protein complex crucial to the photosynthesis of purple sulfur bacteria thriving in ...

Imagine a cancer treatment that precisely targets malignant cells, leaving healthy ones untouched. Consider, also, a cancer treatment that corrects abnormal protein synthesis to produce healthy ...

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

In frame translation initiation sites within coding sequences drive the expression of N-terminally truncated proteoforms.