The above results showed that the metabolomic differences between C33A and CaSki cells were relatively obvious, especially in lipid metabolism, which might be related to the decreased expression of ...

Impact of loss of PRLHR on aneuploidy and initiation of bladder cancer. PPARG protein expression in advanced urothelial carcinoma and selection for response to FX-909, a first-in-class PPARG-targeting ...

However, mechanistic studies to support the conclusion that mitochondrial function is increased in the tumours remain incomplete and would benefit from experiments that would directly interrogate ...

Gene sequencing of these D1.1 viruses has found a mutation that helps the virus copy itself more efficiently into the cells of mammals, including people. This change hasn’t been seen in other D1 ...

Feb. 7, 2025 — A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 ...

PPARG protein expression in advanced urothelial carcinoma and selection for response to FX-909, a first-in-class PPARG-targeting agent. This is an ASCO Meeting Abstract from the 2025 ASCO ...

The following is a summary of “Evaluating lipid-lowering drug targets for full-course diabetic retinopathy,” published in the February 2025 issue of British Journal of Ophthalmology by Cao et al.

While the virus is generally found in wild birds and poses risk only to poultry, its spread to a new range of mammals may pave the way for new mutations that could increase its lethality. In 2024, the ...