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Postprandial increases in insulin and glucose levels stimulate mTORC1 to phosphorylate USP20 at S132 and S134; USP20 is recruited to the HMGCR complex and counteracts its degradation. In ...

PDX Partners, Inc. provides voice over Internet protocol services. It markets its services through direct sales, as well as online. The company was founded in 1997 and is based in Indianapolis ...

The mechanistic Target of Rapamycin complex 1 (mTORC1) senses intracellular amino acid levels through an intricate machinery, which includes the Rag GTPases, Ragulator and vacuolar ATPase (V-ATPase).