Parkinson's disease, Cholesterol

Scientists Just Found a Cholesterol Clue That Could Change Parkinson’s Treatment
A breakthrough study has uncovered a hidden player in Parkinson’s disease—24-OHC, a cholesterol metabolite that fuels the spread of harmful protein clumps in the brain. Researchers found that high levels of this metabolite accelerate neuron damage and motor dysfunction,
Cholesterol Metabolite Implicated in Parkinson’s Disease Pathology
Researchers suggest drugs that prevent cholesterol from being converted to 24-OHC might therefore be an effective treatment for Parkinson's disease.
Cholesterol metabolite linked to Parkinson's disease development in mice
Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice.
Cholesterol metabolism byproduct linked to Parkinson's disease
Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice. Published in the journal PLOS Biology,
Cholesterol Metabolite Linked To Parkinson's Disease Progression, Study Finds
A groundbreaking study by researchers at Wuhan University, China, has identified a cholesterol metabolite that plays a crucial role in the progressio
Parkinson's breakthrough as cholesterol by-product shown to play 'pivotal' role in disease progression
Parkinson’s disease may be linked to a cholesterol by-product that helps harmful protein clumps spread in the brain, a breakthrough study has revealed. Researchers discovered that having excess levels of the metabolite speeds up neuron damage and motor decline.
Cholesterol by-product linked to Parkinson’s disease
Chinese scientists say preventing cholesterol from being converted to 24-OHC might be an effective treatment for Parkinson's disease. The post Cholesterol by-product linked to Parkinson’s disease appeared first on Talker.
ScienceAlert1mon
Parkinson's Discovery Suggests We Could Already Have an FDA-Approved Treatment
Researchers have discovered how a cell surface protein called Aplp1 can play a role in spreading material responsible for Parkinson's disease from cell-to-cell in the brain.
Nature27d
Parkinson's disease articles from across Nature Portfolio
During the pathogenesis of Parkinson’s disease (PD), α-synuclein pathology may originate in peripheral organs and spread to the CNS. Using human tissue samples and multiple approaches in mouse ...
Physics World6h
Wireless deep brain stimulation reverses Parkinson’s disease in mice
A photothermal, nanoparticle-based deep brain stimulation system restored motor skills in mice with Parkinson’s-like disease ...
Medical Xpress15d
The link between renal failure and Parkinson's disease: Researchers illuminate the underlying mechanisms
Recent studies also showed that LBDs, particularly Parkinson's disease, often initiate in ... To identify the organs where α-synuclein pathology begins, we stained the peripheral organs and ...
Armed robbery in Revesby1d
Cholesterol Byproduct Tied to Parkinson's Risk
Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of ...