Le Lézard2d
Gilead's Seladelpar Granted Conditional European Marketing Authorization for the Treatment of Primary Biliary Cholangitis
Gilead Sciences, Inc. today announced that the European Commission (EC) has granted conditional marketing authorization for seladelpar for the treatment of primary biliary cholangitis (PBC) in ...
BioSpace2d
Gilead’s Seladelpar Granted Conditional European Marketing Authorization for the Treatment of Primary Biliary Cholangitis
Outside of the EEA, seladelpar was granted accelerated approval by the U.S. Food and Drug Administration (FDA ... Seladelpar is an oral PPAR-delta agonist, or delpar, for the treatment of PBC.
pharmaphorum2d
Gilead snaps up MiroBio and its checkpoint agonists for $405m
That hasn't stopped the drugs from racking up billions of dollars in annual sales of course, and Gilead will be hoping that MiroBio's approach of targeting immune inhibitory receptors will have ...
pharmaphorum3d
Novo Nordisk nears EU okay for oral GLP-1 drug Rybelsus after CHMP nod
The EMA's main advisory committee has backed approval of Novo Nordisk's oral GLP-1 agonist Rybelsus, a key pipeline drug in its type 2 diabetes franchise. Rybelsus (semaglutide) is the first GLP-1 ...
Medscape6d
Drug-Drug Interactions With Glucagon-like Peptide-1 Receptor Agonists
The Annals of Pharmacotherapy. 2012;46(5):710-717. PubMed was queried (to December 5, 2011) using the search terms exenatide, liraglutide, albiglutide, and lixisenatide. The search was limited to ...
Medscape6d
Hepatic Fibrosis -- Role of Hepatic Stellate Cell Activation
As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...