Investing2d
Cardiol Therapeutics reports heart failure treatment progress
Additionally, ex vivo and in vitro studies revealed that cannabidiol's cardioprotective effects might be linked to the activation of peroxisome proliferator-activated receptor gamma (PPAR-γ ...
Ever-Growing USA on MSN11d
VivaSlim Reviews (Official Website Report) Safe Ingredients For Healthy Weight Loss or Negative Side Effects?
VivaSlim is a natural weight loss supplement that releases stored fat and inhibits its unnecessary storage. It features a ...
PharmiWeb1d
Gilead’s Seladelpar Granted Conditional European Marketing Authorization for the Treatment of Primary Biliary Cholangitis
Gilead Sciences, Inc. (Nasdaq: GILD) today announced that the European Commission (EC) has granted conditional marketing authorization for seladelpar for the treatment of primary biliary cholangitis ...
Health.com20d
9 Vegetables That Can Cause Inflammation
Kayla Girgen, RD, is a licensed dietitian who specializes in weight management and weight loss for patients after bariatric surgery. Inflammation is the body's response to a harmful substance ...
Primary Biliary Cholangitis Clinical Trial Pipeline 20+ Companies Pioneering The Future Of Treatment
Primary Biliary Cholangitis Clinical Trial Pipeline Pharmaceutical companies are advancing the Primary Biliary Cholangitis treatment pipeli ...
BMJ17d
PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage
uhnresearch.ca Objectives We have previously shown that peroxisome proliferator-activated receptor gamma (PPARγ), a transcription factor, is essential for the normal growth and development of ...
Frontiers20d
Polyphenols: immunonutrients tipping the balance of immunometabolism in chronic diseases
In energy-depleted states, activated AMPK typically inhibits mTOR signaling and promotes mitochondrial biogenesis via the peroxisome proliferator-activated receptor-gamma (PPARγ) co-activator-1 alpha ...
Frontiers20d
Protective Effects of Bile Acids Against Hepatic Lipid Accumulation in Hybrid Grouper Fed a High-Lipid Diet
Notably, aconitate hydratase_A0A6I9PAY1 (involved in the pathway: tricarboxylic acid cycle, glyoxylate, and dicarboxylate metabolism) and gamma-enolase-like_A0A6I9PPR6 ... A0A6J2QQI0 (butanoate ...
Nature18d
PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
Peroxisome proliferator-activated receptor-γ (PPAR-γ) is a ligand-dependent nuclear receptor that has a critical role in adipogenesis, glucose metabolism and placental function 1,2,3.
eLife11d
Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...
The Lancet22d
Peroxisome proliferator-activated receptor α as a novel therapeutic target for schizophrenia
dDepartment of Molecular Brain Science, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan eLaboratory for Molecular Mechanisms of Brain Development, RIKEN Center for ...