Meghan Markle has received a much-needed good publicity boost from an author "friend" following some damning reviews of her latest cookery and lifestyle show which has been slated as "fake". The ...

PIP3 recruits AKT to the cell membrane, where AKT is activated through phosphorylation by PDK1 at T308 and by mTORC2 at S473. Activated AKT phosphorylates TSC1/2 and relieves its inhibition ...

The German marque was present alongside the other nine incumbent teams at the O2 in London last week as it unveiled an all but unchanged design scheme on a show car. But while several sides had ...

Formula 1 has taken over London’s O2 Arena to host a group launch for all 10 teams to mark the sport’s 75th anniversary. ‘F1 75 Live at The O2’ begins at 5:30 GMT and you can follow all ...

BMP4 is a key growth factor well known in promoting bone regeneration and has been reported to be able to regulate T cell development in the thymus. Here, we showed that BMP4 downregulates the ...

The Pten phenotype is mimicked by constitutive activation of PI3 kinase and is rescued by the removal of PDK1 (PDPK1), but does not depend on the downstream kinases AKT and mTORC1. High resolution ...