The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

While several scientific reports have revealed the distinct regulatory mechanisms of osteoclast and osteoblast differentiation, little is known about the common factors that influence the ...

Previous research has highlighted the role of osteogenic CpG oligodeoxynucleotide (iSN40) in promoting osteoblast differentiation and supporting bone formation. A new study reveals that iSN40 also ...

The structural integrity of bones has been attributed to bone remodeling-aa highly regulated process of bone formation and bone resorption (dissolving old and damaged bones), driven by osteoblast ...

In this study, we identify inhibition of osteoblast (OB) function as an additional pathogenic mechanism in CCL3-induced bone disease. MM-derived and exogenous CCL3 represses mineralization and ...