Progressive encephalopathy with edema, hypsarrhythmia, and optic nerve atrophy (PEHO) syndrome is a rare, apparently autosomal recessive condition in which characteristic dysmorphic features are ...

The boy was conscious and oriented. Aside from the bilateral optic disc edema, the general neurologic examination, including that of other cranial nerves, was nonfocal. Ophthalmologic examination ...

It’s painless, but eye doctors examining people with the condition can see optic nerve swelling, which normally resolves in six weeks. The symptoms can range from mild to severe. “ ...

Cross-section of nerve fibers from the mouse optic nerve: The dark dense lines show the insulating layer, the myelin. Highlighted in red is a swollen, clogged area of an impaired nerve fiber ...