According to the World Health Organization (WHO), over 22% of the global population smokes, with more than 9 million smoking-related deaths reported annually. Effective treatments to alleviate ...

biomarker identification to link nicotine abuse liability with the upregulation of nicotinic acetylcholine receptors (nAChRs), a critical indicator of addiction; and neurophysiological evaluation ...

Pain is an example of an important sensory neuron. When you feel pain from a hot pan or a sharp pin, you are sending sensory information via sensory neurons up to the brain. The flow of electrical ...

Nicotine molecules bind to the body’s nicotinic acetylcholine receptors, which are involved in regulating the dopamine reward system, and the resulting feel-good sensation is what makes nicotine ...

the researchers traced the problem to reduced activation of nicotinic receptors by acetylcholine, another neurotransmitter important for decision-making. The study helps to explain the ...

While previous research has highlighted the key role of the cNTS in food intake regulation, the unique contribution of the different neuron subtypes within this brainstem region and the mechanisms ...

Study of 2.4 million participants reveals potential advantages for cardiometabolic and psychiatric conditions alongside increased risks of gastrointestinal and musculoskeletal issues Study ...

Department of Pharmaceutical Sciences, Medicinal Chemistry Section “Pietro Pratesi”, University of Milan, Via L. Mangiagalli 25, Milan 20133, Italy ...

Neuronal pathway finding is crucial for structured ... Released from target tissues and neurons Specific tyrosine kinases receptors Aloisi, 2003 Semaphorin family (Classes 3 to 7 in vertebrates ...

Finally, we provide evidence for acetylcholine receptor nicotinic acetylcholine receptor alpha 6 (nAchRalpha6 ... and shows the contribution of the neuronal cholinergic signaling to the immune system ...