General and Administrative (G&A) Expenses. G&A expenses for the three months ended March 31, 2025 were $6.9 million compared to $5.1 million for the same period in 2024. The increase was primarily ...

Solute carrier family 25 member 19 (SLC25A19) is a transporter protein of thiamine pyrophosphate across cellular membranes, which is needed as a cofactor for multiple metabolic enzymes and is ...

There is no standard of care for fibrolamellar liver cancer, no targeted therapies. But that may be changing, thanks to ...

As Ho, Yu and colleagues report in the current issue of Cancer Discovery, PLT012 undermines the metabolic checkpoint mediated ...

As Ho, Yu and colleagues report in Cancer Discovery, PLT012 undermines the metabolic checkpoint mediated by CD36 to restore ...

A new study has identified a specific mode of fat uptake by immune cells within tumors that serves as a metabolic checkpoint against anti-cancer immune responses.

Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...

Removing EPO signaling in mouse liver tumors leads to tumor regression along with sensitivity to immunotherapy.