Microglia play a crucial role in neuroinflammation after ischemic brain injury. Previous data have shown that leukocyte immunoglobulin-like receptor B4 (LILRB4) was upregulated in mice after middle ...

DiaMedica Therapeutics Inc. (Nasdaq: DMAC), a clinical-stage biopharmaceutical company focused on developing novel treatments for severe ischemic diseases, today announced the peer-reviewed ...

In any case, there was no mortality signal associated with alteplase administered up to 24 hours after a stroke in HOPE.

In an editorial, J. Mocco, MD, of Mount Sinai Health System in New York City, characterized the DISTAL and ESCAPE-MeVO cohorts as being older and having higher baseline disability, which may have ...

Stroke experts from UCSF Health presented new research and clinical findings at the annual the American Stroke Association’s International Stroke Conference (ISC25), the world’s premier meeting ...

Although the terminal internal carotid artery occlusion is relatively easy to identify, there is often a debate as to what constitutes a proximal (involving the M1 segment) versus a distal (involving ...

The cyclists — they came to be known as the Kanata 5 — were in a marked bike lane. The driver, Sommit Luangpakham , would tell an ...

Methods: Both sexes of C57BL6 healthy young were subjected to 30 or 60-minutes transient endovascular filament middle cerebral artery occlusion (MCAO). For homogeneity of all other factors, we used ...

Light has long been recognized as a critical regulator of human health, influencing everything from hormone secretion to cardiovascular rhythms. Published in the journal, Journal of Thrombosis and ...

Ultrasound is used to assess blood flow velocity to the head either at the middle cerebral artery using TCD ultrasound or at the external carotid artery via extracranial ultrasound. NIRS supplies an ...

1–7 However, they focused on anterior LVO involving the internal carotid artery and proximal middle cerebral artery (MCA). The HERMES collaboration, a meta-analysis of five RCTs (MR CLEAN, ESCAPE, ...

In this study, we used Adeno-associated vectors carrying Netrin-1 gene (AAV-NT-1) to up-regulate the expression level of Netrin-1 in rats’ brain after middle cerebral artery occlusion (MCAO). We found ...