The abstracts feature 12-month data from the first three adult patients in our ongoing Phase 1/2 trial of OPGx-LCA5, as well as pre-clinical results on OPGx-MERTK and OPGx-RDH12. An abstract ...
2 Immunology Research Core Facility – Gemelli Science and Technology Park (GSTeP) - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy 3 Division of Clinical Immunology, Fondazione ...
We investigated the role of MerTK, a receptor tyrosine kinase responsible for myeloid cell clearance of dead cells, in the regulation of DC function and metabolism in the tumor microenvironment.
Following staining for MertK (MertK-PE/Cyanine7, Invitrogen, 2555774), flow cytometry was performed to determine the effect of LNP-MertK on macrophages. Nystatin, a decreasing endocytic reagent, was ...
Reverse docking results revealed that MerTK might be the real target of TP. TP (CAS number 38748-32-2, purity >98%) was purchased from MedChemExpress (Shanghai, China). LPS (L2755) was purchased from ...
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