Relapsed/refractory (R/R) mature T and natural killer (NK)-cell lymphomas (TNKL) are aggressive blood cancers often resistant to frontline therapies. A team of Mass General Brigham researchers found ...

A highly sensitive bone marrow test could double survival rates for some groups of younger adults with acute myeloid leukemia ...

USC researchers have developed an innovative type of cancer-fighting immune cell, the EchoBack CAR T-cell, that uses focused ...

Researchers sought to determine whether MSD HSCT or auto-HSCT would have advantages over chemotherapy in post-remission treatment for patients with AML.

Results: Mast cells with low BTG2 expression were identified in the metastatic lymph nodes and in situ tumor of the NAC-resistant group. Mast cells with low BTG2 expression have enhanced migratory ...

Indeed, a subtype of AML—acute promyelocytic leukemia (APL)—is already treated this way using a pair of drugs (all-trans retinoic acid and arsenic trioxide) that shove APL cells down the ...

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Recovery after a stem-cell transplant typically requires a hospital stay of several weeks. Recipients may experience side effects. If you or a loved one has been diagnosed with Acute Myeloid Leukemia ...

At this time, many differential diagnoses were considered, including mastocytosis. A CT-guided bone biopsy showed mast cells that were positive for CD25, along with elevated mast cell tryptase levels, ...

It also appeared to trigger a pro-inflammatory state involving white blood cells, inflammatory proteins ... diet,” study author Quirijn de Mast, MD, PhD, internist-infectious disease specialist ...

BCR signaling plays a crucial role in the pathogenesis of CLL. 2,9,10 Activation of this pathway fosters an ideal leukemic microenvironment, promoting CLL cell proliferation and survival. 2 BCR ...

Laboratory investigations showed mast cell infiltration ... vital for improving outcomes in this rare and aggressive form of leukemia,” the authors of the report wrote.