Fosun Pharma continues to uphold the internationalization strategy in multiple dimensions, such as innovative R&D, licensing, manufacturing and operations as well as commercialization. In 2024, ...

Today Briony takes a look at the new Zotac MEK1 Mini PC - a system that promises to bring great gaming performance in a small, console sized chassis. The big question ...

1Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. 2Human Oncology Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, ...

Zotac's MEK1 Gaming PC. Check out all of our CES 2018 Coverage: <a href="https://www.thinkcomputers.org/tag/ces-2018/">https://www.thinkcomputers.org/tag/ces-2018/</a ...

Researchers from the University of Muenster described the preclinical efficacy of zapnometinib, a selective MEK1/2 inhibitor, against H5N1 clade 2.3.4.4b.

4 Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China 5 Department of Etiology and Carcinogenesis, National Cancer Center/National Clinical Research ...

This pathway, and particularly MEK1/2, are therefore promising therapeutic targets. Assessment of target engagement is crucial to determine pharmacodynamics or the efficacy of a MEK1/2 inhibitor. In ...

The gray horizontal panel shows the activity profile of the 28 kinase inhibitors against MEK1, where the compounds are ordered based on their relative potencies against MEK1. The green and purple ...

Angiogenesis requires the temporal coordination of the proliferation and the migration of endothelial cells. Here, we investigated the regulatory role of microRNAs (miRNAs) in harmonizing angiogenesis ...

KCa2.1, KCa2.2, KCa2.3 and KCa3.1 constitute a family of mammalian small- to intermediate-conductance potassium channels that are activated by calcium-calmodulin. KCa3.1 is unique among these four ...