The liver, located in the upper right side of the abdomen, is the body’s largest organ and one of the most important. The liver performs hundreds of vital functions, including converting ...

Cirrhosis is a condition in which scar tissue gradually replaces your healthy liver cells. It usually happens over a long period, often due to hepatitis, alcohol use disorder, or metabolic ...

3 National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd ... activity was measured by microfluorimetric assays in normal and polycystic cholangiocyte cultures from humans ...

RIPK1 deficiency in hepatocytes sensitizes the liver to short-term fasting-induced liver injury and hepatocyte apoptosis. (A) Serum alanine amino-transferase (ALT) levels. (B) Serum aspartate ...

The discovery that RIPK1 deficiency sensitizes the liver to acute injury and hepatocyte apoptosis is based on convincing evidence, highlighting the importance of RIPK1 in maintaining liver homeostasis ...

Akero Therapeutics reported Monday strong results from a nearly two-year, placebo-controlled study showing its drug efruxifermin reversed liver scarring in patients with cirrhosis caused by the ...

Chronic hepatitis infections can lead to complications such as cirrhosis, liver cancer, and liver failure. A cancerous tumor or tumors that occur in hepatocytes ... Intrahepatic Cholangiocarcinoma A ...

Elevated liver enzymes can occur for many reasons. Most often, elevated liver enzymes are temporary and resolve on their own without treatment. Occasionally, elevated liver enzymes require additional ...