A young girl faces an uncertain future after she was diagnosed with an extremely rare and debilitating medical condition which has 'put a timeline on her life'.

Stem-cell differentiation is the process by which a more specialised cell is formed from a stem cell, leading to loss of some of the stem cell's developmental potential. Stem-cell differentiation ...

Personalised heart failure therapy may soon become feasible for LMNA, alongside personalised risk stratification, as variant-related differences in phenotype severity and clinical course are being ...

As a crucial cellular process involved in degrading and recycling damaged organelles and proteins, autophagy-related (ATG) proteins mediated autophagy plays a significant role in various physiological ...

Lamin A and lamin C (encoded by LMNA, MIM 150330) are widely expressed in somatic cells, and diverse LMNA mutations cause various disorders, laminopathies, including diseases affecting striated and ...

Cx40 (connexin 40) was reported to be a molecular modulator of the renal baroreflex. 6 Connexins are transmembrane gap junction proteins involved in cell-to-cell communication. Renin cell-specific ...