Patients with solid tumors other than mesothelioma must have local available data for loss-of-function NF2/LATS1/LATS2 genetic alterations (truncating mutation or gene deletion; LATS1/LATS2 mutations ...
Laboratoire de Physique de l’Ecole Normale Supérieure LPENS, ENS, PSL Research University, CNRS, Sorbonne Université, Université de Paris, Paris, France Inovarion, Paris, France High Throughput qPCR ...
TEAD4 (TEA Domain Transcription Factor 4) is well recognized as the DNA-anchor protein of YAP transcription complex, which is modulated by Hippo, a highly conserved pathway in Metazoa that controls ...
Request permissions for this article. Eppley Institute for Research in Cancer and Allied DiseasesUniversity of Nebraska Medical Center Omaha NE USA Fred & Pamela Buffett Cancer CenterUniversity of ...
This month's cover highlights the article Immune cells adapt to confined environments in vivo to optimise nuclear plasticity for migration by Helen Weavers and Tua Karling. The cover features confocal ...
Figure. MST1-Cx43 axis in disturbed flow (d-flow) mediated endothelial cell-cell communication and vascular dysfunction. Key findings show that disturbed flow (d-flow) inhibits MST1 kinase that allows ...
Bladder cancer (BC) is one of the world’s most frequent cancers. Surgery coupled with adjuvant platinum-based chemotherapy is the current standard of therapy for BC. However, a high proportion of ...
Angiogenesis involves extensive remodelling of the extracellular matrix (ECM) and endothelial cells (ECs) (Stupack and Cheresh, 2002). The ECM is important for dynamic and multifunctional regulation ...
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