By targeting surface markers on cancer cells, engineered synthetic receptors expressed on immune cells can be directed to ...

Department of Nuclear Medicine, School of Medicine & Health, Klinikum rechts der Isar, TUM University Hospital, Technical University of Munich, Ismaninger Strasse 22, Munich 81675, Germany Central ...

Integrins are transmembrane glycoproteins that ... a function of LC3 triggered by integrin LFA1 outside-in signaling, which activates AMPK to drive the co-clustering of LFA1 and LC3, thereby ...

The impact of the hinge domain (HD) and the transmembrane domain (TMD) between the extracellular antigen-targeting CARs and the intracellular signaling modalities of CARs has not been systemically ...

Faculty of Physics, Astronomy and Applied Computer Science, M. Smoluchowski Institute of Physics, Jagiellonian University, Łojasiewicza 11, Kraków 30-348 Poland Doctoral School of Exact and Natural ...

Objective This study aimed to investigate the role of transmembrane emp24 domain-containing protein ... the ADP-ribosylation factor 1/ extracellular signal-regulated kinase ½ signaling pathway.

Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008.

integrin, and amyloid precursor protein (APP), while the latter includes ephrin-B and neuropilin-1 (Nrp1). As canonical receptors do not possess enzymatic activity in their cytoplasmic domains, the ...