Integrins are transmembrane glycoproteins that ... a function of LC3 triggered by integrin LFA1 outside-in signaling, which activates AMPK to drive the co-clustering of LFA1 and LC3, thereby ...

et al., 2016). FIGURE 3. Glucose, lipid, and amino acid metabolism pathways and integrin-mediated mechanotransduction by HIF signaling. Transmembrane protein integrins serve as molecular linkage ...

Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...

BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.

By targeting surface markers on cancer cells, engineered synthetic receptors expressed on immune cells can be directed to ...

This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...

The influenza A virus genome consists of eight segments of single-stranded, negative-sense viral RNA, which encode multiple ...

TNF receptor 1 (TNFR1) is expressed in most cell types, and can be activated by binding of either soluble TNF (solTNF) or transmembrane ... of TNFR1-mediated signaling while sparing TNFR2 ...

Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008.

What if we could design proteins that mimic nature’s signaling mechanisms but with ... to analyze and redesign the interactions between transmembrane helices and solvent molecules within the ...

Department of Nuclear Medicine, School of Medicine & Health, Klinikum rechts der Isar, TUM University Hospital, Technical University of Munich, Ismaninger Strasse 22, Munich 81675, Germany Central ...