Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK ...

In molecular mechanism study, we found that COL10A1 interacts with DDR2 and affects the downstream FAK signaling pathway to regulate LUAD cell ... against anti-collagen X (ab58632) and anti-integrin ...

In conclusion, KLX exhibits protective effects against EndMT and atherosclerosis by activating the FGFR1/MAP4K4 pathway and suppressing the integrin β1/TGFβ signaling pathway. This study's ...

Like other musculoskeletal tissues, articular cartilage is populated by mechanosensitive cells (chondrocytes), which signal via highly analogous pathways. Alfredson and Lorentzon treated 57 ...

Department of Nuclear Medicine, School of Medicine & Health, Klinikum rechts der Isar, TUM University Hospital, Technical University of Munich, Ismaninger Strasse 22, Munich 81675, Germany Central ...

As results, the disruption of cadherin signaling has significant ... Wnt/β-catenin or other signaling pathways. Bartolomé et al. pointed out that the Arg-Gly-Asp motifs of VE-cadherin activate the ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Despite tremendous improvement in the development of tissue-regenerating materials, a ...

They also show that PLECTIN is key for HCC invasion and metastasis. They show a correlation between PLECTIN inhibition and attenuated FAK, MAPK/ERK, and PI3K/AKT signaling. The most common primary ...