Single cell transcriptomic analysis and cytokine measurements supported these results showing increased production of CCL5, CXCL9, CXCL10 and IFNg in the EphA2 KO tumors. Analysis on tumors at very ...

The antiviral transcriptional response in circulating immune cells is strongly associated with a specific subset of IFNs, most prominently IFNA2 and IFNG. In contrast, proteomics signatures indicative ...

X-axis is position along the chromosome. Y-axis is –log10(p). A) Juicebox plot showing contact frequency map of the region on Chromosome 12 around the IL-22 and IFNG genes. Blue boxes are regions ...

Interferon gamma (IFN-γ) is a cytokine that induces a series of immune responses against viruses and tumors. The pro-apoptotic, anti-tumor and anti-proliferative actions of the cells are ...

Mucosal-associated invariant T (MAIT) cells belong to a family of innate-like T cells that bridge innate and adaptive immunities. Although MAIT cells have been implicated in tumor immunity, it ...

BMP4 is a key growth factor well known in promoting bone regeneration and has been reported to be able to regulate T cell development in the thymus. Here, we showed that BMP4 downregulates the ...