We emphasize the functional role of adaptors in signal transduction in macrophages and their influence on the phenotypic transition of macrophages from pro-inflammatory M1-like states to anti ...

These effects are achieved through IRF-mediated control of gene expression, leading to changes in how cellular nutrients are used via metabolic pathways. M1 macrophages turn to aerobic ...

A van fire brought traffic to a standstill on the M1 in Leicestershire this afternoon (Wednesday, February 26). All lanes on the northbound carriageway had been closed between Junction 20 ...

Here’s the latest traffic and travel news from around Northern Ireland. The M1 eastbound is closed between junctions eight and nine, just beyond Moira, due to a traffic collision. PSNI are in ...

The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

ABU DHABI, 7th February, 2025 (WAM) -- Sheikh Abdullah bin Bayyah, Head of the Abu Dhabi Forum for Peace and Chairman of the UAE Council for Fatwa, highlighted the UAE's role as a global model of ...

As of January 2025, the seasonally adjusted M1 money supply according to the Federal Reserve. An increase in the supply of money typically lowers interest rates, which generates more investment ...

We show that DNA-PK acts as a pattern recognition receptor, binding cytoplasmic DNA and triggering the transcription of type I interferon (IFN), cytokine and chemokine genes in a manner dependent on ...