The search words include “hypoxia and HIF”, “HIF and breast cancer”, “HIF and angiogenesis and breast cancer”, “HIF inhibitor and breast cancer”, sorted by “best match”. Search results were selected ...

§ p = 0.0001 between temsirolimus and IFN-α. ¶ p = 0.0001. # p = 0.0001. ** p = 0.001. NR: Not reported; ORR: Overall response rate; OS: Overall survival; PFS ...

Moreover, HIF-1α is involved in many oxLDL-induced effects in macrophages including inflammatory response, angiogenesis and metabolic reprogramming. OxLDLs activate toll-like receptor signaling ...

Here, we report a novel Hif-3α variant, Hif-3α2, in zebrafish. Hif-3α2 lacks the bHLH, PAS, PAC, and ODD domains, and is expressed in embryonic and adult tissues independently of oxygen availability.

Because bioinformatic analysis confirmed that miR-206 carries the 5′-GGAAUG-3′ ‘seed’ region, which is the putative binding site of the 3′-UTR region of HIF-1α, and the aforementioned ...