Many drugs from different chemical classes and therapeutic areas have been shown to inhibit currents mediated via the hERG-coded ion channel, which is strongly correlated to a risk of inducing TdP.

While hERG channel is notoriously regarded as an off-target due to drug-induced cardiotoxicity, its therapeutic potential as a drug target remains largely unexplored. Methods: This study investigated ...

2010-2013: project associate - Regulation of overflow metabolism in filamentous fungi (FWF-project P22220); project completed (PhD-student: Anja Krüger) 2012-2015: project leader - Abiotic stress in ...

Jennifer Love Hewitt’s hindsight is 20/20. The “Ghost Whisperer” actress reflected on being sexualized as a teen and having “grown men” make jokes about her breasts during her appearance ...

Shanghai Frontiers Science Center of Drug Target Identification and Delivery, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai 200240, China State Key Laboratory of ...

Department of Nanoscale Science and Engineering, College of Nanotechnology, Science and Engineering, University at Albany, Albany, NY, United States The evolution of stem cell-based heart models from ...

Standardized dried extracts listed according to their phytochemical marker employed for standardization and supplier. The analytical solutions of such dried extracts solutions were coded as: Hp, Gb, ...

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