Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

Diamyd Medical announced today that Anna Styrud, CFO, has decided to step down from her position. During her 15 years as CFO, she has successfully navigated the financial markets and played a key role ...

Diamyd Medical will receive USD 1.75 million in expanded collaboration support from Breakthrough T1D (formerly JDRF), the world's leading Type 1 Diabetes ...

Here, the authors use full-length Mpro protein as substrate and demonstrate ... attention mechanism to simultaneously predict peptide–HLA and peptide–TCR bindings. Experiments verify that ...

By targeting surface markers on cancer cells, engineered synthetic receptors expressed on immune cells can be directed to ...

Developing effective treatments and understanding how the mechanism of the immune system have always been challenging for ...

Get Instant Summarized Text (Gist) Water molecules are crucial in assisting transcription factors to read and regulate the human genome. These proteins bind to specific DNA sequences, often in non ...

The influenza A virus genome consists of eight segments of single-stranded, negative-sense viral RNA, which encode multiple ...

Diamyd Medical will receive USD 1.75 million in expanded collaboration support from Breakthrough T1D (formerly JDRF), the world's leading Type 1 Diabetes research and advocacy organization, in support ...

Junk' RNA Segments Play Role in Protein Production, Cell Stress Response Feb. 11, 2025 — Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional ...

Intranasal vaccination is a desired route for protection against influenza viruses by mucosal and systemic immunity. However, the nasal mucosa impedes the intranasal delivery of vaccines. Here, we ...