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However, removing Grb2’s putative Shp2 dephosphorylation site (Y209 ... Conversely, we observed that FGF-induced Shc phosphorylation hinges on the FGFR juxtamembrane domain rather than its Frs2 ...

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The battle over the Jio Hotstar domain has taken an unexpected turn, with the website now acquired by two Dubai-based siblings, Jainam and Jivika, days after its original owner—a Delhi-based anonymous ...

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The Src homology 2 (SH2) domain has a special role as one of the cornerstone examples of a “modular” domain. The interactions of this domain are very well-conserved, and have long been described as a ...

Activation of Rab35 was assessed by GST-pulldown. The interaction of DENND1A and Grb2 was assessed by GST-pulldown and co-immunoprecipitation assays. The relationship between DENND1A and cell ...

Delayed SH2 domain recruitment correlated with clustering of SH2 domain ... After normalization, EGFR no longer dominated binding. Only three domains (GRB2, SHCA PTB and to a lesser extent ARG) ...