Gastrointestinal involvement is common among patients with EGPA, with eosinophilic tissue infiltration, weight loss, and ...

In this report, we present a typical case of granulomatosis with polyangiitis (GPA) complicated by spontaneous renal hemorrhage (SRH), a rare but potentially severe condition. The patient developed ...

group and Wegener's granulomatosis (WG) is immune complex (IC) mediated, there are no simultaneous data on circulating IC, complement levels and deposits of Ig and complement in the kidney.

Granulomas are small lumps of immune cells that form in your body in areas where there is infection or inflammation. They’re most commonly found in your lungs, but they can also be in other ...

Introduction: This study aimed to identify new clinical phenotypes of microscopic polyangiitis (MPA) using a principal components analysis (PCA)-based cluster analysis. Methods: A total of 189 ...

Others, such as eosinophilic granulomatosis with polyangiitis, tend to develop in adults. Symptoms of autoimmune vasculitis can vary depending on the type of condition and which parts of your body ...

Iptacopan hydrochloride (Fabhalta) is a factor B inhibitor of the alternative complement pathway15-17 ... cytoplasmic antibody-associated vasculitis (ANCA Vasculitis), granulomatosis with polyangiitis ...

The complement system is an important part of the humoral immune defence in mammals that is formed by about 35 soluble and cell-surface proteins. Together these proteins enable the host to ...