N. gruberi normally lives as a little amoeba that only makes microtubules during cell division—in particular to build the mitotic spindle. However, when the amoeba is stressed, it can change into a ...

Cilia-and flagella-associated protein 221 (CFAP221), also known as ... central pair; PMTs, peripheral microtubules; ODA, outer dynein arm; IDA, inner dynein arm; DNAAFs, dynein axonemal assembly ...

The articles in this special issue highlight the diversity and complexity of research into reproductive health, including the need for a better understanding of the fundamental biology of reproduction ...

Microtubules are cylindrical polymers composed of alpha and beta tubulin. They are a major component of the cytoskeleton and mediate crucial cellular functions including formation of the mitotic ...

Cilia are outgrowths of the plasma membrane of eukaryotic cells that contain a specialised cytoskeleton. Motile cilia are present on multiciliated cells and use this cytoskeleton to move fluid ...

Male mice lacking either XAP5 or XAP5L display infertility, as a result of meiotic prophase arrest and sperm flagella malformation, respectively. Mechanistically, XAP5 positively regulates the ciliary ...

The ciliary compartment consists in the axoneme and the ciliary membrane. The axoneme is a cylindrical structure of microtubules extended from the basal body, a specialized centriole structure, to the ...