A recent review highlights how the Mediterranean diet can reduce inflammation and improve outcomes for chronic skin ...

the authors show how STAMBPL1 promotes TNBC angiogenesis via a feed-forward GRHL3/HIF1a/VEGFA axis. They demonstrate that STAMBPL1 interacts with FOXO1, define the required domains in each protein, ...

Jun proto-oncogene (C-Jun), mammalian target of rapamycin complex 1 (mTORC1), neurogenic locus notch homolog protein 2 (Notch2), polypyrimidine tract-binding protein 1 (PTBP1), peroxisome ...

Elon Musk on Thursday made a plea for “top notch” air traffic controllers to come out of retirement to help ease a shortage of skilled aviation workers as public concern over flight safety mounts.

"There is a shortage of top notch air traffic controllers. If you have retired, but are open to returning to work, please consider doing so," Musk, who heads the Department of Government ...

Three Notch Medical Center is now under new leadership as Dr. Corbin Ferguson bought all rights to the practice from Dr. Frank Maddox last week on Wednesday, Feb. 19. A Birmingham native, Ferguson ...

TV presenter Miquita Oliver has revealed her first childhood kiss was with ISIS Beatle Jihadi George - a high-profile terrorist whose heinous crimes sparked outrage across the world. The former ...

Human mutations in Notch signalling components have been implicated in several forms of congenital cardiovascular disease, including cardiac outflow tract defects (jagged 1, notch 2), aortic valve ...

The research aims to identify key molecular and mutational events in thyroid, adrenal and other endocrine tumors, and their clinical applications in endocrine pathology and molecular pathology for ...

Programmed cell death protein 1 (PD-1)/PD-ligand (L)1, the immune checkpoint inhibitors have emerged as a promising strategy for the treatment of various diseases including chronic liver diseases ...

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, and can be subcategorized histologically and/or based on PAX-FOXO1 fusion gene status. Over the last four decades, there have ...

Here, we demonstrate that induced endothelial-specific depletion of the transcription factor Forkhead Box O1 (FoxO1) in male mice led to increased vascular density in adipose tissue. Upon high-fat ...