Ventricular tachycardia is an abnormally fast heart beat (with three or more consecutive heart beats at least 100 beats per minute) that originates from one of the ventricles in the heart. The ...
the authors show how STAMBPL1 promotes TNBC angiogenesis via a feed-forward GRHL3/HIF1a/VEGFA axis. They demonstrate that STAMBPL1 interacts with FOXO1, define the required domains in each protein, ...
AKT regulates the cell cycle by phosphorylating FoxO1 and decreasing its transcription of CDK inhibitors p21 and p27. AKT, protein kinase B; CDK, cyclin dependent kinase; FoxO1, forkhead box O1 ...
2019). The PAX-FOXO1 transcription factor, which is both upstream to many of the signal cascades that promote RMS tumorigenesis, is a direct and promising target, although inhibitors that bind to ...
2020). Figure 7. S100A11-HDAC6-FOXO1 axis in the regulation of autophagy and lipogenesis in liver induced by high fat diet. Dietary lipids induce the overexpression of S100A11. S100A11 then competes ...
Here, we demonstrate that induced endothelial-specific depletion of the transcription factor Forkhead Box O1 (FoxO1) in male mice led to increased vascular density in adipose tissue. Upon high-fat ...
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