Frontiers22d
ACKR4 Recruits GRK3 Prior to β-Arrestins but Can Scavenge Chemokines in the Absence of β-Arrestins
Chemokines are essential for guiding cell migration. Atypical chemokine receptors (ACKRs) contribute to the cell migration process by binding, internalizing and degrading local chemokines, which ...
Medical Xpress26d
Advances in corneal healing research drive new treatments for rare eye diseases
Get Instant Summarized Text (Gist) Research is advancing treatments for rare eye diseases, which are a leading cause of untreatable blindness in Europe. Seven rare ocular conditions affecting the ...
EurekAlert!26d
Advances in corneal healing research drive new treatments for rare eye diseases
In vivo laser axotomy of a single subbasal fiber (SBF) in an adult mouse. The Ocular Neurobiology laboratory at the Institute for Neurosciences, a joint center of Miguel Hernández University (UMH ...
eLife29d
Synaptic plasticity in the medial preoptic area of male mice encodes social experiences with female and regulates behavior toward young
Red-shifted color indicates a higher density of cFos-positive neurons. paternal (n = 8), virgin (n = 3) (G) AAV5-EF1α-DIO-eYFP was injected into the Me of Cartpt-Cre mice. Representative images of ...
Frontiers1y
Transdermal tibial nerve optogenetic stimulation targeting C-fibers
Methods: Ten rats were injected with AAV2/6-hSyn-ChR2(H134R)-EYFP into the tibial nerves. Transurethral cystometry was performed 4 weeks after the virus injection. Illumination (473-nm blue light at ...
eLife3y
Impaired spatial learning and suppression of sharp wave ripples by cholinergic activation at the goal location
To this end, we optogenetically controlled the activity of cholinergic neurons using ChAT-Ai32 crossbred mice that expressed enhanced YFP-tagged channelrhodopsin-2 (ChR2-eYFP) under the control of the ...