Cogent Biosciences, Inc. (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined diseases, today announced four preclinical poster presentations at ...

The observational study measured how physicians changed treatment plans after seeing HER2DX results and how patients did on the new plans.

A real-world study showed HER2DX guided treatment changes in approximately 48% of HER2-positive breast cancer cases.

REVEAL GENOMICS ®, a pioneering Barcelona-based biotech company dedicated to advancing precision oncology, is proud to announce the publication of a groundbreaking study demonstrating the clinical ...

Here, we characterize and compare efficacy, phenotypic subpopulations and modes of action of CAR-CIK cells and conventional CAR-T cells from same-donor samples in ErbB2+ rhabdomyosarcoma (RMS).

Methods: Here, we assess the efficacy of clinically usable CAR-engineered NK cell line NK-92/5.28.z against ErbB2-positive RMS in vitro and in a metastatic xenograft mouse model. Results: Our results ...

Higher tumor-infiltrating lymphocyte (TIL) levels were independently associated with improved overall survival in patients with early-stage ERBB2-positive breast cancer. Each 5% increase in TILs ...

Attribution (BY): Credit must be given to the creator. The ErbB2 signaling pathway plays a crucial role in cancer stem cells (CSCs), governing cancer aggressiveness and proliferation. Targeting ErbB2 ...

A decision on approval is expected in the third quarter of 2025. The US Food and Drug Administration (FDA) has granted priority review to the new drug application for zongertinib to treat adults ...

"We believe zongertinib has the potential to transform the care of previously treated patients with HER2 (ERBB2)-mutant advanced non-small cell lung cancer and are hopeful about the continued research ...

The decision is intended for individuals who have undergone a previous systemic therapy and have tumours with human epidermal growth factor receptor 2 (HER2) (ERBB2) mutations. A Prescription Drug ...