This poster introduces the background of Ubiquitins, applications of Ubiquitins in research, and featured active Ubiquitins ...

GRANT PARK — Chill out this weekend in Grant Park as the village will be holding a fun event. The village of Grant Park’s Festival Committee will be holding the 10th annual Cabin Fever Reliever ...

CRL4 (Cullin-RING ubiquitin ligase) is an E3 ubiquitin ligase, composed of three subunits DDB1, cullin 4 (CUL4), and regulator of cullins 1 (RBX1/ROC1). This enzyme has great importance in ...

Sussex Drug Discovery Centre, School of Life Sciences, University of Sussex, Falmer BN1 9QJ, U.K. Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, 1 James ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Biomolecular interactions are essential in many biological processes, including ...

Chronic hepatitis B virus (HBV) infection imposes a severe burden on global public health. Currently, there are no curative therapies for millions of chronic HBV-infected patients (Lok et al., 2017).

At least 250 million people worldwide are chronically infected with HBV, a small hepatotropic DNA virus that replicates through reverse transcription. Chronic infection greatly increases the risk for ...

This study provides important computational insights into the dynamics of PROTAC-induced degradation complexes, offering a convincing demonstration that differences in degradation efficacy can be ...

Department of Chemistry, University of California, Riverside, Riverside, United States Department of Bioengineering, University of California, Riverside, Riverside, United States ...