Commit is developing its Bispecific Complement Engaging (BiCE) platform, which uses single domain antibodies that bind to the complement protein C1q to activate and direct the complement system ...

The work presented here introduces a biological nanopore formed by the self-assembly of complement component 9 (C9). This exceptionally large and cylindrical protein pore is composed of 20 ± 4 ...

The analysis revealed significant binding interaction between Fam102a and karyopherin subunit alpha 2 (Kpna2)—a protein that transports molecules across the nuclear membrane. This finding ...

It directly interacts with the complement system, which is key to innate immunity ... such as C1INH, factor I (FI), C4 binding protein (C4BP), and FH, which are available in serum. Membrane-bound ...