Research reveals that DNA mutations may influence epigenetic clocks, raising new questions about the aging process.

The root causes of most forms of Alzheimer's disease largely remain a mystery. Now, researchers have revealed a new piece of the puzzle. Neurogeneticists at the University of Florida led by Lien ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

This paper addresses the important question of quantifying epistasis patterns, which affect the predictability of evolution, by reanalyzing a recently published combinatorial deep mutational scan ...

The flagship of the RAS(ON) inhibitors is the nigh-unpronouncable daraxonrasib, designed to block any activated KRAS, including any of the many, many potential codon mutations (G12C, G12D ...

Viralgen and Axovia Therapeutics are set to form a partnership to progress the development and manufacturing of an adeno-associated virus vector serotype 9 (AAV9)-based gene therapy for retinal ...

Their findings, published in Nature Aging, describe a never-before-seen link between the two most accepted explanations: random genetic mutations and predictable epigenetic modifications.

Summary: A new study has uncovered a direct link between somatic mutations and epigenetic modifications, challenging established views on aging. Researchers found that random genetic mutations drive ...

Health authorities and researchers are closely examining the mutations found in the virus extracted from the 65-year-old man, who was infected through contact with backyard birds contaminated by ...

A human strain of H5N1 bird flu isolated in Texas shows mutations enabling better replication in human cells and causing more severe disease in mice compared to a bovine strain. While the virus isn’t ...

Study finds surprising way that genetic mutation causes Huntington's disease, transforming understanding of the disorder Researchers studying brain cells from Huntington's patients show that the ...