Aurora kinase A activity is inhibited by BRCA1. PLK1 induces CDC25C activation and WEE1 degradation as well as regulates NIMA-related-kinase 2 (NEK2) activity. NEK2 phosphorylates CEP250 and mediates ...

Regulated hydrolysis of the phosphoinositide phosphatidylinositol(4,5)-bis-phosphate to diacylglycerol and inositol-1,4,5-P 3 defines a major eukaryotic pathway for translation of extracellular cues ...

Meiosis is a specialized cell cycle that requires sequential changes to the cell division machinery to facilitate changing functions. To define the mechanisms that ...

The G2/M checkpoint is regulated by a tight balance of phosphorylation and dephosphorylation events, where Cdc25c plays a crucial role in the onset of mitosis (Draetta and Eckstein, 1997). p30 ...

Wintering Monarch butterflies (Danaus plexippus), Santa Cruz, California. Masses of migrants gather in eucalyptus groves to overwinter before returning north; their numbers have decreased as a ...