Virax Biolabs Group Limited ("Virax" or the "Company") , an innovative biotechnology company focused on the detection of immune responses and diagnosis of viral diseases, today announced it has ...

CD39 and AXL. For more information about Arcus Biosciences’s clinical and preclinical programs, please visit www.arcusbio.com.

Adenosine is a pleiotropic immunosuppressive substance, produced mainly by the enzymes CD39 and CD73, from extracellular immunogenic ATP. Thus, CD73-rich tumors may experience decreased anti-tumor ...

Markers such as PD-1 and CD39 are commonly used to identify tumor-reactive TILs, yet these empirically derived markers can produce false positives or fail to capture rare tumor-reactive populations.

This month's cover highlights the article Boosting human immunology: Harnessing the potential of immune organoids by Dirk Baumjohann and Maximilian Moll. The review article explores recent advances in ...

ligand-gated cation channels termed P2X receptors), enzymes such as ectonucleotidases (CD39, CD73, CD203, CD38), ADP-ribosyltransferase (CD296 or ART1), adenosine deaminase, and nucleotide kinases), ...

B cells, particularly Breg cells, can induce maternal tolerance by producing IL-10 or the CD39/CD73 pathway (13). Immune dysregulations from each type of cells are associated with RPL. In unexplained ...

Single-cell measurements of cellular characteristics have been instrumental in understanding the heterogeneous pathways that drive differentiation, cellular responses to signals, and human disease.

Interleukin-1 (IL-1) consists of two distinct forms (IL-1α and IL-1β) and is a master cytokine of local and systemic inflammation (Dinarello et al., 2012). Primarily produced by monocytes, macrophages ...

Anti-murine PE-Cy7-conjugated CD11b mAb (clone M1/70) was from BD Biosciences. PerCP-Cy5.5-conjugated F4/80 mAb (clone BM8) and eFluor660-conjugated CD39 Ab (clone 24DMS1) were from eBioscience.