eLife11d
Expression of a single inhibitory member of the Ly49 receptor family is sufficient to license NK cells for effector functions
A novel mouse model offers definitive evidence that a single inhibitory receptor family governs the critical natural killer cell functions of licensing and missing-self.
BMJ22d
POS0452 ABNORMALITY OF TYPE I INTERFERON SIGNALLING IN B CELLS IN PRIMARY SJÖGREN´S SYNDROME AND THE IMPACT ON LABORATORY AND CLINICAL FINDINGS
Results Compared to HC the pSS group showed significantly elevated STAT1 expression among all B cell subsets (p>0.0001) including naïve (CD27-IgD+), pre-switched (CD27+ IgD+), switched-memory ...
The Motley Fool28d
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eLife1y
Single-cell characterization of human GBM reveals regional differences in tumor-infiltrating leukocyte activation
This study is valuable and contains results that are supported by convincing evidence. In the future, the observations could be further strengthened by independent validation, and by looking at larger ...
Frontiers2y
Study of CD27, CD38, HLA-DR and Ki-67 immune profiles for the characterization of active tuberculosis, latent infection and end of treatment
Objective: To compare the capacity of CD27, HLA-DR, CD38 and Ki-67 markers to characterize LTBI, active TB and patients who ended treatment and resolved TB. Methods: Blood was collected from 45 ...
Frontiers4y
Markers of T Cell Exhaustion and Senescence and Their Relationship to Plasma TGF-β Levels in Treated HIV+ Immune Non-responders
Maturation subsets were determined based on expression of CD45RA and CD27; naïve = CD45RA+CD27+; central memory (CM) CD45RA-CD27+; effector memory (EM) CD45RA-CD27-; terminal effector memory (TEM) ...