In patients with castration-resistant prostate cancer (CRPC), clinical resistances such as androgen receptor (AR) mutation, AR overexpression, and AR splice variants (ARVs) limit the effectiveness of ...
2020b; Xie et al., 2020). Human PCa cell lines (22RV1 and DU145) and kidney cell line (293T) were purchased from ATCC. 22RV1 and DU145 cells were cultured in 1640 and Dulbecco modified Eagle medium ...
The chemokine receptor CXCR4 and its ligand CXCL12 play an important homeostatic function by mediating the homing of progenitor cells in the bone marrow and regulating their mobilization into ...
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