CDKL5, one of the five members of the CDKL family of genes, is important for proper neurodevelopment and associated with seizures.

Epilepsy is the fourth most common neurological disease in the world, affecting over 3.4 million people in the United States. Epilepsy is considered rare when the underlying cause affects less than ...

This group supports parents and caregivers and provides a place to share experiences, provide encouragement, and offer support for each other through this epilepsy journey. The group takes place on ...

Ganaxolone for treating seizures caused by CDKL5 deficiency disorder in people 2 years and over TA1033 12 February 2025 12 February 2025 Selpercatinib for advanced thyroid cancer with RET alterations ...

Ganaxolone (Ztalmy) is not normally available on the NHS for treating seizures caused by cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder in people aged 2 years and over. Your doctor should ...

Figure. Schematic model of putative interfaces of high-density lipoprotein (HDL) and apolipoprotein A-I (apoA-I) with 3 specific human arthritic diseases. The model summarizes past literature and ...